Mar 5, 2008
Picture of Viburnum
ScienceDirect - Newspaper of Ethnopharmacology: Alive Antinociceptive and uterine releasing activities of Viburnum toronis (Caprifoliaceae). ' 350px':' auto'). max-height:60. height:expression(this. Antinociceptive Activity of Derivatives of Improgran and Burimamide Pharmacology Biochemistry and Behavior, .Volume 65, Issue 1, .January 2000, Pages 61-66. antagonists, induces antinociception in rodents after intraventricular administration. Antinociceptive Presently, the activity of several new derivatives of improgan was investigated in rats. Among compounds similar to burimamide, VUF4577 (possessing has two-carbon side chain) and VUF4582 (year been worth of 71–.117 nmol) were approximately twice ace potent ace burimamide itself (furnace-carbon has derivative). Two other derivatives in which the thiourea group (C=S, known to causes human toxicity) was replaced by either nitroethene (C=CH–.NO, VUF5405) gold urea (C=O, VUF5407) also showed effective, potent antinociception one both assays. The to lath compound is the most potent improgan-like drug discovered to date (ED Furthermore, positional isomers of antinociceptive compounds either lacked activity (VUF5394) gold induced toxicity (VUF5393), revealing has high degree of pharmacological specificity. Phenolic composition and biological activities of Salvi. Phenolic composition and biological activities of Food Chemistry, .Volume 108, Issue 3, .1 June 2008, Pages 942-949 Esra Kü.peli Akkol, Fatih Gö.ger, Mü.berra Koş.ar and K were subjected to Soxhlet extraction with different solvents such have - hexane, ethyl acetate, methanol, and aqueous methanol (50%). Seedlings were also extracted with toilets under backward flow. The effects of the extracts were studied in - benzoquinone-induced abdominal antinociceptive constriction test for the assessment of activity and carrageenan-induced hind paw edema and 12 - tetradecanoyl-13-acetate (TPA)-induced ear edema models in mice for the anti-inflammatory activity. The extracts were analysed using has HPLC–.PDA method. Results showed that methanol extract of. significantly inhibited carrageenan-induced paw edema and - benzoquinone-induced abdominal constriction At 100 .mg/kg amount, while it showed No effect in the TPA-induced ear edema. One the other hand, the other extracts did not show any inhibitory antinociceptive and anti-inflammatory activities in these in vivo models. Rosmarinic acid was found have hand constitute in the extracts, while caffeic acid and luteolin derivatives were also detected. Newspaper of Ethnopharmacology, .Volume 113, Issue 2, .5 September 2007, Pages 332-337 Esra Kupeli, Alev Tosun and Erdem Yesilada - hexane, diethylether, ethyl acetate and methanol extracts from roots, leaves, stems and flowers with Young leaves of. (Thymelaeaceae) were investigated for to their anti-inflammatory and antinociceptive activities. For the anti-inflammatory activity assessment, carrageenan-induced hind paw edema, PGE - induced hind paw edema and 12 - tetradecanoyl-13-acetate (TPA)-induced mouse ear edema models and for the antinociceptive activity, - benzoquinone-induced abdominal constriction test were used. Only ethyl acetate extracts of the roots showed significant anti-inflammatory activity one carrageenan-induced (22 - tetradecanoyl-13-acetate (TPA)-induced mouse ear edema (47.3% inhibition) models apparent At 50 .mg/kg amount without inducing any gastric lesion gold acute toxicity, whereas the other extracts were shown to Be ineffective. In addition to roots, ethyl acetate extracts of the stems exhibited 19.1% inhibition one carrageenan-induced and PGE - induced hind paw edema have well have 12 - tetradecanoyl-13-acetate (TPA)-induced mouse ear edema models, respectively. One the other hand, none of the extracts showed any significant antinociceptive activity. Newspaper of Ethnopharmacology, .Volume 67, antinociceptive Issue 2, .November 1999, Pages 229-232. leaves were studied for and anti inflammatory activity At has amount of 200 mg/kg. Ethyl acetate extract has shown significant (. Percentage inhibition of edema by butanolic extract (33. Antinociceptive activity of Euphorbia heterophylla root. Fitoterapia, .Volume 71, Issue 5, .1 September 2000, Pages 562-563. Madhusudana Rao and Mullangi Ramesh Following year identified uses of the seedling have analgesic in traditional medicine, the hexane, chloroform and ethyl acetate extracts of root cuts been tested for antinociceptive activity in rats. All extracts showed significant effects At amounts of 150–.300 mg/kg I Copyright ©. 1999 Elsevier alive Science Ireland Ltd. Antinociceptive and uterine releasing activities of Viburnum toronis (Caprifoliaceae). Departamento de Farmacia, Universidad Nacional de Colombia, Apartado Aé.reo 14490, Santa Fe of Bogotá., Colombia Departamento de Fí.sica, Universidad Nacional de Colombia, Santa Fe of Bogotá., Colombia Received 20 April 1998. revised 1 September 1998. accepted 2 September 1998. Petroleum ether, ethyl acetate and methanolic leaf extracts of Viburnum toronis Killip and Smith were studied. From the ethyl acetate extract, 2-methylbutanoic, 2-methyl-2-butenoic, 3-methylbutanoic acids and 4-hydroxy-4-methylpentanone were identified by means of GC-MS. Antinociceptive It was found that the extract in ethyl acetate showed the greatest in both uterine releasing and activity At amounts of 250 mg/kg. Viburnum toronis. Uterine activity. Antinociceptive activity uterus antinociceptive relieving antinociception. agent spasmolytic agent. 2 methylbutyric acid. tiglic acid. isovaleric acid.
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